Thymidine (symbol dT or dThd), also known as deoxythymidine, deoxyribosylthymine, or thymine deoxyriboside, is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA.

Thymidine is a pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. It has a role as a metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a thymine. It is an enantiomer of a telbivudine.

2005年6月13日 · Thymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in...

Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. Here, we present the protocol to synchronize cells at G1/S boundary by using double thymidine block.

Thymidine is a nucleoside consisting of thymine and deoxyribose. When a phosphate group is covalently attached to the sugar, it forms a nucleotide. An example of a nucleotide wherein three phosphate groups are attached to thymidine is thymidine triphosphate (TTP), one of the building blocks of DNA synthesis.

Thymidine is also referred to as pyrimidine deoxynucleoside. Deoxythymidine is a nucleoside present in DNA. In a DNA double stranded structure, thymidine pairs with deoxyadeninosine. It is useful in cell synchronization during S-phase. In the salvage pathway of pyrimidines, pyrimidine phosphorylase reversibly converts thymine to thymidine.

Thymidine analogs are typically used as proliferation markers, to label dividing cells permanently and to pass labeling on to the progeny. Most early studies used tritiated thymidine, which is incorporated into the DNA of dividing cells during S-phase of mitosis and can be detected autoradiographically (Altman and Das, 1965; Cameron et al., 1993).

Thymidine kinase 1 (TK1) is a DNA salvage pathway enzyme involved in regenerating thymidine for DNA synthesis and DNA damage. Thymidine is transferred from the extracellular space across the cell membrane by facilitated diffusion and is converted to its monophosphate form (dTMP) within the cytosol by TK1 [ 1 , 2 ].

2024年7月31日 · What is the difference between thymine and thymidine? Thymine is one of four nitrogenous bases in DNA whereas thymidine is a nucleoside that has thymine attached to a deoxyribose sugar. Key Areas Covered

Thymidine, or deoxythymidine, is one of the four nucleosides constituting DNA. Its unique structure and properties make it indispensable in the formation and stabilization of the DNA double helix. This substance consists of the pyrimidine base thymine attached to …