The human gastrointestinal (GI) tract harbours a complex and dynamic population of microorganisms, the gut microbiota, which exert a marked influence on the host during homeostasis and disease. Multiple factors contribute to the establishment of the ...

The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. [4]

2023年2月15日 · The gut microbiota exists symbiotically within the human digestive system and helps support energy harvesting, digestion, and immune defense.

2023年8月18日 · You have some gut microbiota in your stomach and small intestine, but most of them are in your large intestine (colon). They float around inside or attach to the mucous lining on the inner walls ( mucosa ).

Abnormal distribution of microbiota in the gut alters intestinal function. Abnormal signals through the parasympathetic nervous system via the vagus nerve to the brain as seen in neurodegenerative diseases affect bowel motility and hormone secretion.

In this review we seek to outline the current state of knowledge on what characterizes a “healthy” or “normal” intestinal microbiome, what factors modify the intestinal microbiome in the healthy state and how the intestinal microbiome affects normal host physiology.

2016年12月15日 · A large number of diverse microbial species reside in the distal gastrointestinal tract, and gut microbiota dysbiosis — imbalances in the composition and function of these intestinal microbes...

In a healthy person, these “bugs” coexist peacefully, with the largest numbers found in the small and large intestines but also throughout the body. The microbiome is even labeled a supporting organ because it plays so many key roles in promoting the …

2024年11月20日 · Having a more varied gut microbiota may promote better health and, in turn, reduce your risk of disease. You can’t just take probiotics to stave off diabetes or treat arthritis.

2018年6月13日 · What does the gut microbiota do? The gut microbiota provides essential capacities for the fermentation of non-digestible substrates like dietary fibres and endogenous intestinal mucus.