H4K16ac is an epigenetic modification to the DNA packaging protein Histone H4. It is a mark that indicates the acetylation at the 16th lysine residue of the histone H4 protein. H4K16ac is …

2023年6月12日 · Here, we demonstrate that the male-specific lethal (MSL)-complex-mediated histone H4 acetylation at lysine 16 (H4K16ac) is enriched at TEs in human embryonic stem …

As well as peaks of acetylated H4K16 and KAT8 histone acetyltransferase at the transcription start sites of expressed genes, we report that acetylation of H4K16 is a new marker of active …

H4K16 乙酰化 （H4K16ac）是一个非常特别的 组蛋白修饰，它不仅可以调节染色体的凝集程度，而且可以直接影响基因的表达。 H4K16乙酰化是由乙酰转移酶MOF介导的。 MOF完全敲除 …

2023年7月21日 · Histone H4 lysine 16 acetylation (H4K16ac), governed by the histone acetyltransferase MOF, orchestrates gene expression regulation and chromatin interaction. …

为了进一步研究早期胚胎发育中H4K16ac的详细作用及机制，2020年6月4日，德国马普研究所Asifa Akhtar团队在2020年6月4日Cell在线发表了题为Intergenerationally Maintained Histone …

Here, the authors show that chromatin at certain transposable elements (TEs) is coated with acetylation at H4K16, which can lead to increased local chromatin accessibility and …

2020年6月5日 · 在这里，通过分析ZGA之前和之后精确分阶段的果蝇胚胎并通过进行遗传和基因组实验，该研究表明H4K16ac是从雌性生殖细胞传代传递的，并且在早期胚胎发生过程中没有正 …

In this study, we set out to investigate the possible contribution of H4K16ac to establishing HSC heterogeneity and propagating this to derived daughter cells of the hematopoietic lineage. …

Here, we demonstrate that the male-specific lethal (MSL)-complex-mediated histone H4 acetylation at lysine 16 (H4K16ac) is enriched at TEs in human embryonic stem cells (hESCs) …