Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic ...

1 Liver Unit, Department of Medicine A, Imperial College School of Medicine, St Mary’s Hospital Campus, South Wharf Street, London W2 1PG, UK 2 Department of Hepatobiliary Surgery, Royal Free Hospital ...

Correspondence to Professor Lee-Yan Sheen, Institute of Food Science and Technology, National Taiwan University, Taipei 106, Taiwan; lysheen{at}ntu.edu.tw and Professor Ming-Shiang Wu, Department of ...

Objective In acute pancreatitis (AP), bacterial translocation and subsequent infection of pancreatic necrosis are the main risk factors for severe disease and late death. Understanding how ...

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

12 Centre for Digestive Diseases, Karolinska University Hospital Huddinge, Stockholm, Sweden 13 Centre for Digestive Diseases, Karolinska University Hospital Solna, Stockholm, Sweden Objective This ...

Non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease worldwide. Understanding the pathological and molecular hallmarks from its first description to ...

Objective We performed a meta-analysis of observational studies to quantify the magnitude of the association between non-alcoholic fatty liver disease (NAFLD) and risk of extrahepatic cancers. Design ...

Correspondence to Professor Bernd Schnabl, Department of Medicine, University of California, San Diego, CA 92093, USA; beschnabl{at}ucsd.edu The spectrum of non-alcoholic fatty liver disease (NAFLD) ...

Objective Increased de novo fatty acid (FA) synthesis and cholesterol biosynthesis have been independently described in many tumour types, including hepatocellular carcinoma (HCC). Conclusion Our ...

Objective Dietary fibres are essential for maintaining microbial diversity and the gut microbiota can modulate host physiology by metabolising the fibres. Here, we investigated whether the soluble ...

Correspondence to Dr Heng Xu, State Key Laboratory of Biotherapy and Cancer Center, Sichuan University, Chengdu, China; xuheng81916{at}scu.edu.cn; Professor Zong-Guang Zhou; zhou767{at}163.com ...