GENFI Top Hits. CSF proteomics linked abundance of CALB2, GRN/NAGA, and PEA15/SEMA6A to C9ORF72 (gold), GRN (red), and MAPT ...
New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...
For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...
"However, the sequence of events and the form of tau that confers toxicity are still unclear, due in large part to the lack of physiological models of tauopathy initiation and progression in which ...
In this study, mouse models of Alzheimer's disease were treated with Xenon gas that has been used in human medicine as an anesthetic and as a neuroprotectant for treating brain injuries. Xenon gas ...
More information: Wesley Nogueira Brandao et al, Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy, Science Translational Medicine (2025). DOI ...