Attempts to reactivate the gene have been challenging, but science has reached the point where early clinical trials are looking at drugs that may impact its function. In addition, those who have ...

A pooled HR and 95% CI were calculated using a random-effects model. Conclusions Patients with OAC and TP53 gene mutations have reduced overall survival compared with patients without these mutations, ...

Here we report a case of a T-cell lymphoma harboring a lentiviral integration in a known tumor suppressor, TP53 ... gene with attendant structural disruption of the gene product.

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Results: A signature based on six optimal candidate genes (TP53, IL-7, PDGFRA, S100B, DLL3, and TP63) was successfully constructed and proved to have good prognostic ability. Through verification, the ...

Furthermore, gender, smoking history, and tumor stage may be correlated with the presence of gene mutations. However, the impact of diabetes on gene mutation ... BRAF, HER2, Tumor Protein 53 (TP53), ...

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Comment from Associate Professor Jun Takayama, Tohoku University School of Medicine "The accuracy validation using the RASEN ...

The bill from Sen. Brandon Shippy, R-New Plymouth, would place a moratorium on “human gene therapy products” until July 2035. The bill defines those as products that include nucleic acids ...

Cardinal Health is unveiling Advanced Therapy Connect, which the company describes as a best-in-market unified ordering portal for cell and gene therapies, through its Advanced Therapy Solutions ...

Jan. 29, 2025 /PRNewswire/ -- CPC (Colder Products Company), part of Dover (NYSE: DOV) and a leading manufacturer of connection technologies used in biopharmaceutical processing, today announced the ...