to prevent K48-linked ubiquitination and degradation of cGAS. Consequently, cGAS evades p62-mediated autophagic degradation and can stimulate type I IFN signaling after viral infection (156). STING ...

Ubiquitination is a PTM characterized by the covalent binding of ubiquitin (Ub) molecule to a specific target protein. This essential PTM primarily determines protein stability by marking the target ...

Patrick Mahomes is a big reason the Kansas City Chiefs have hoisted the Vince Lombardi Trophy in back-to-back seasons. He was named the Super Bowl MVP after winning each of those championships ...

Fox News viewers were given an unexpectedly honest look at the potential toll of the tariffs announced by President Donald Trump on Saturday and how the decision may impact them personally by ...

A claim circulating on social media that a bee sting will increase the size of one's penis is FALSE. The claim widely shared in WhatsApp forums indicated that by one subjecting their genitalia to ...

Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...

Lisa Wellman, D-Mercer Island, wants to bring it back with Senate Bill 5282. If approved, the board must submit annual reports detailing the MECTF’s reactive and proactive sting operations, with ...

Ubiquitin is an intracellular signalling molecule that is conjugated to various proteins. Ubiquitin conjugation to itself yields Lys- or Met-conjugated chains, thus expanding its repertoire of ...

During Monday’s interview, Davis reiterated that the Police Department is not actively participating in the stings but that it’s normal for local and federal operations to intersect when there ...