Trial results demonstrated that the peptide was at least as effective as conventional antibiotics, but did not show it was significantly better. As a result, the FDA refused approval in July.

Discover the importance of antibiotics, bacterial cell walls, and resistance mechanisms in fighting bacterial infections effectively.

Antibiotic-resistant bacteria have become a major threat to public health. The World Health Organization estimates that 1.27 ...

To enable clinical use for the peptide material, particularly in combination with standard treatments such as antibiotics, the researchers had to ensure that the material does not negatively ...

Researchers from The University of Manchester have discovered a new way of manipulating key assembly line enzymes in bacteria which could pave the way for a new generation of antibiotic treatments.

A new ally is emerging in the increasingly urgent battle against superbugs – and you might have encountered it before at the ...

Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the bacteria are not resistant? In their latest study, researchers challenge the ...

For technical reasons, the English full text will be published approximately two weeks after the German print edition has been published. 1. Hornef MW, Wick MJ, Rhen M et al.: Bacterial strategies ...

July 2, 2024 — A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making ...

This is in vivo tracking of bioluminescently labeled (live) bacterial infections. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by ...

Keywords structure function and engineering of polyketide synthases hybrid polyketide/non-ribosomal peptide antibiotics and anticancer drugs polyketide based cholesterol lowering agents Areas of ...