Merck Sharp & Dohme LLC has identified targeted activator of cell kill (TACK) compounds acting as Gag polyprotein (HIV-1)/protein Pol dimerization inducers reported to be useful for the treatment of ...

The simple quantitation of HIV-specific antibody by ELISA or Western Blot after vaccination is not sufficient owing to the vast majority of this antibody being nonprotective. Thus assays must ...

另一个重要发现是HIV-1病毒基因组中关键的“移码位点”附近的复杂RNA结构。这个移码位点对于这种病毒产生两种关键蛋白Gag和Gag-Pol的正确比例至关 ...

这个移码位点对于病毒产生正确比例的两种关键蛋白Gag和Gag- pol至关重要，这两种蛋白是组装感染性颗粒和HIV-1复制所必需的。研究人员证明，这种延伸的RNA折叠不仅促进了上游位置的核糖体碰撞——一种似乎调节翻译的机制——而且还保持了移框效率。Caliskan ...

If left untreated, human immunodeficiency virus (HIV) almost always will progress to AIDS, even after many years. The immune defenses become compromised and the body is less able to defend itself ...

Get Instant Summarized Text (Gist) Some HIV vaccines trigger the immune system to produce antibodies against immune complexes rather than directly targeting the virus. This phenomenon occurs after ...

Gag and Gag-Pol, which are necessary for assembling infectious particles and replication of HIV-1. The researchers demonstrated that this extended RNA fold not only promotes ribosome collisions ...

Gag and Gag-Pol, which are necessary for assembling infectious particles and replication of HIV-1. The researchers demonstrated that this extended RNA fold not only promotes ribosome collisions ...

Pol Pot and his henchmen inflicted unprecedented carnage, genocide, forced labor camps, and sickness, claiming about 2 million lives, or about a third of this country’s population, after seizing ...

Many of the fears have been fueled by media reports which either overstate the risk of acquiring HIV through accidental occupational needlestick injuries or spotlight cases in which victims are ...