Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...

It was found that NAD or the nicotinamide adenine dinucleotide is the fuel for the cellular engines which is necessary for the proper functioning of the body. However, an enzyme called CD38 breaks ...

ART1- mediated ADP-ribosylation of T cells can trigger an apoptotic cascade resulting in NAD-induced cell death (NICD), and subsequently tumour immune escape [2]. The ectonucleotidase CD38, is ...

CARsgen Therapeutics Holdings Limited, a company focused on innovative CAR T-cell therapies for the treatment of hematologic malignancies and solid tumours, announces that KJ-C2320, an allogeneic CAR ...

Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme ubiquitously present in all living cells, playing a pivotal ...