When STING is triggered, TANK-binding kinase (TBK1 ... “This paper shows the good and bad activity coming from different parts of the protein. So conceivably, you can selectively manipulate either one ...

A study published in the journal Molecular Cell has shed light on the multifaceted role of STING, a protein previously ...

Work at IFM Due Inc. has led to the identification of stimulator of interferon genes protein receptor (STING; TMEM173) antagonists reported to be useful for the treatment of cancer, systemic lupus ...

The discovery of a protein’s contribution to the development of T-cells in the spleen and thymus could lead to new treatment strategies for immunodeficiency diseases. Despite its name ...

prod STING to trigger type I IFN production and elicit an innate immune response. 12 In particular, Chen was elated to find that DNA activated cGAS in a way that was independent of DNA sequence. “It ...

How does the body react to insect bites or stings? Female mosquitoes bite because they need the protein in blood to develop ...