Emerging evidence suggests that autophagy plays a crucial role in regulating and fine-tuning cGAS-STING signaling. Reciprocally, cGAS-STING pathway members can actively induce canonical as well as ...

We studied the role of the cGAS–STING pathway in the IFN-I-producing cascade driven by SLE serum. Methods We collected sera from patients with SLE (n=64), patients with other autoimmune diseases (n=31 ...

Centromere defects, chromosome instability, and concomitant cGAS-STING pathway activation correlate with increased fibrosis markers, suggesting that the cGAS-STING pathway is linked to immune ...

Tumor immune evasion mechanisms could be reversed by activating intracellular antiviral immune responses. It has been reported that the use of DNA methyltransferase (DNMT) inhibitors combined with ...

View Full Profile. Learn about our Editorial Policies. When STING is triggered, TANK-binding kinase (TBK1) activates and leads to interferon production. However, Tan and his team wanted to identify ...

Sting from a scorpion Onset of local pain and tingling after a scorpion is seen in the area The main symptoms are pain, tingling and numbness at the sting site About 85% cause only local symptoms at ...

Stings from bees, wasps and hornets can be painful. To treat a sting and help relieve the pain, dermatologists offer these tips. It can happen fast. One minute the kids are all playing peacefully ...

Sting has postponed multiple concerts due to a temporary throat infection. On Tuesday, the veteran musician's team took to social media to announce the postponement, along with rescheduling ...

Sting has canceled an upcoming appearance and postponed three shows amid an ongoing illness. “On advisement from his doctor, due to illness, it is with sincere regret that Sting must cancel his ...

A phenomenon upon release, ‘Desert Rose’ was an inspired fusion of Algerian folk music and contemporary electronica that became a high-water mark for Sting. Alluring and sensual, Sting’s ...

8. As for the Aug. 21 Citi Field show, it will serve as the debut at the Mets’ new home for both Joel and Sting. Neither has played the Flushing venue since its 2009 opening. However ...