It is an ester-derived prodrug that is converted in vivo by serum and tissue esterases to tenofovir, an acyclic nucleoside phosphonate (nucleotide) that inhibits HIV reverse transcriptase.

The early lineages of hexapods (broadly defined insects) have long been debated. Researchers at University of Tsukuba and ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

Candidate genetic variants included in a genetic risk algorithm may not meet standards of reasonable clinical efficacy in identifying opioid use disorder risk, according to a study published in JAMA ...

Cystic-fibrosis-focused Sionna Therapeutics made its public debut this week, with an upsized public offering. Meanwhile, Titan America had a ...

For all of last year, Illumina’s net loss grew 5% from $1.161 billion to $1.223 billion, on revenue that fell 3% from $4.505 ...

The early lineages of hexapods (broadly defined insects) have long been debated. Researchers at University of Tsukuba and collaborators critically examined the newly proposed "Protura-sister" ...

Modern agriculture’s critical challenge is to feed a growing global population while reducing the environmental footprint of ...

Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

An interview with Glenn Saxe, computational psychiatrist, on the limitations of our current diagnostic system, and how causal ...

相比于SNVs和indels，SVs往往涉及更大范围的基因组重排，可能会影响到多个基因及其调控区域。以往的基因组研究大多集中于研究单个碱基的变异，如SNVs，它们与疾病的关系早已得到了大量的证实。然而，结构变异由于其较低的发生频率和复杂的遗传模式，长 ...