Single-cell RNA sequencing (scRNA-seq) research of mouse and human CD8 + T cells revealed a surprising population of distinct age-related CD8 + T cells (5). Similarly, scRNA-seq from aged and young ...

As a metabolic center, the liver prevents inappropriate immune responses to abundant dietary antigens within the liver that could result in liver injury. This self-preservation mechanism can however ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

The paper illustrates a valuable approach to generating TCR transgenic mice specific for known epitopes. Solid evidence validates the described pipeline for identification of TCRs from single-cell ...

Institute for Advanced Optics, Hunan Institute of Science and Technology, Yueyang, Hunan 414006, China School of Information Science & Technology, Hunan Institute of Science and Technology, Yueyang, ...

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, ...

Therefore, after a review of the available values found in the literature, we performed direct measurements from samples stained by multiplex IHC to study the composition of fibroblasts and ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal ...

but stimulates production of neutralising antibodies that are ineffective against the virus used in the human challenge study. This allowed the scientists to assess how well the T-cells ...