Our study investigated resistance evolution under stimulatory antibiotics and uncovered new genetic mechanisms of resistance linked to metabolic remodeling. We documented a shift from a fast, ...

In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from the University of Michigan has used simulations on the Pittsburgh ...

As the global population continues to grow, innovative solutions are needed to ensure food security. With limited land and ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

Melanism is a genetic mutation characterized by an overproduction of melanin, the pigment responsible for the dark coloration ...

However, it rarely occurs in other cancer types, thus highlighting the need for large-scale analysis of rare cancers to identify the distinct mutations that underpin their evolution.

Dr. Paulo H. Verardi, a virologist and head of the Department of Pathobiology and Veterinary Science at the University of ...

The researchers compared the observed mutations based on vaccination policies. Some countries, such as China, implement extensive vaccination campaigns, while others prefer to limit these ...

"The Chinese poultry lineage may have experienced more vaccine-driven selection compared to other lineages," the researchers ...