Studies suggest that diet affects the gut microbiota, which subsequently influences the metabolome ... This work was supported by Project NIH UH2/3 DK083981 and administrative supplement 04S1 (GDW, ...
Human studies rarely, if ever, employ prebiotics. A prebiotic is shown to be efficacious in animal studies: typically 10% w/w of the diet, which in humans equates to about 50 g per day.18 However, as ...
There are two main sites of BA biosynthesis, hepatocytes and gut microbiota. BAs are synthesized in the liver as primary BAs such as cholic acid (CA), chenodeoxycholic acid (CDCA) and their conjugated ...