LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Attribution (BY): Credit must be given to the creator. Endonuclease III (EndoIII), a key enzyme in the base excision repair (BER) pathway, contains a [4Fe4S] cluster that facilitates DNA repair ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.

DUB, deubiquitinating enzyme; E1, ubiquitin-activating enzyme; E2, ubiquitin-binding enzyme; E3, ubiquitin ligase; USP, ubiquitin-specific protease; UCH, ubiquitin COOH terminal hydrolase; MJD, ...

Using DNA nanorobots, the researchers were able to influence the shape and functionality of these synthetic cells. New transport channels for proteins and enzymes DNA nanotechnology is one of ...

Figure 3 pUL13 phosphorylated the antiviral factor SAMDH1 Thr592 to promote viral replication. Inhibiting the dNTP enzyme activity of the sterile alpha motif and HD domain ... The conserved ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Using DNA nanorobots, the researchers were able to influence the shape and functionality of these synthetic cells. New transport channels for proteins and enzymes DNA nanotechnology is one of Laura Na ...

A method for genetically barcoding Drosophila is developed and used to tag defined cell populations in vivo for single-cell transcriptomics experiments and to enable multiplexed behavioral analysis.

Advances in DNA nanotechnology now offer promising solutions ... this system can facilitate the transportation of therapeutic proteins or enzymes to their targets in the cell.