Many DNA polymerases also have an additional intrinsic proofreading exonuclease activity ... the switch from initiation to leading- and lagging-strand synthesis, the successful replication ...

Mitochondrial DNA (mtDNA) replication is essential for mitochondrial function. This is carried out by a dedicated DNA polymerase gamma, with 5’–3’ polymerase and 3’–5’ proofreading/ exonuclease ...

The RNA Institute, University at Albany, State University of New York, Albany, New York 12222, United States Department of Nanoscale Science and Engineering, University at Albany, State University of ...

Modulation of T-cell activation is therefore a potential strategy to target inflammation in atherosclerosis. Ubiquitination is an important regulatory mechanism of T-cell activation and several E3 ...