Reaction 1 converts ammonia to the intermediate, hydroxylamine, and is catalyzed by the enzyme ammonia monooxygenase. Reaction 2 converts hydroxylamine to nitrite and is catalyzed by the enyzmer ...
We have demonstrated the cytochrome P-450 dependent production of hydroxylamine metabolites of the sulphonamides by murine microsomal preparations. In order to pursue the role of such a metabolite ...
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