The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

Tuesday, shares of Ideaya Biosciences (NASDAQ:IDYA), trading at $22.18 near its 52-week low of $22.10, drew attention as BTIG analysts maintained their Buy rating and $62.00 price target. According to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Homologous recombination (HR) is important for ...

To our knowledge, there are no existing investigations employing a separation protocol resembling the helicase dissociation process of DNA. Helicases break hydrogen bridges in a helicoidal-sequence ...

and SCLC patient case study IDE275 (GSK959), a potential first-in-class Phase 1 Werner Helicase program targeting MSI-high solid tumors Targeting presentation at a medical conference with GSK ...