ranging from DNA replication to chromatin remodelling. Fuelled by the binding and hydrolysis of nucleoside triphosphates, helicases move along nucleic acid filaments and separate double-stranded ...

T cells play a pivotal role in the immune system by transforming into powerful effector cells that combat pathogens. This transformation requires rapid proliferation, during which DNA replication ...

The RNA Institute, University at Albany, State University of New York, Albany, New York 12222, United States Department of Nanoscale Science and Engineering, University at Albany, State University of ...

DNA damage can result in the genetic sequence being misread and copied during cell division -- known as DNA replication -- and ... can make a different mistake, leading to multiple different ...

Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

Given that the designed higher-ordered DFNs utilized the same DNA scaffold strand with identical sequences, the variations in their reaction kinetics should lie in the differences of their topological ...

It is therefore likely that Myt1 overexpression partially counteracts processes initiated by Wee1 or Chk1 inhibition leading to single stranded DNA and subsequent ATR activation. The original ...

Mechanistically, replication stress and BRCA1 deficiency lead to significant upregulation of ELF3 expression. ELF3 can help suppress excessive genomic instability and promote LP transformation with ...

If you'd like to learn more about your health, heritage and family history, an at-home DNA test can help you do just that. Justin Jaffe is the Managing Editor for CNET Money. He has more than 20 ...