"Our study set out to fill this gap in the literature, by examining whether changes in DNA methylation could serve as the biological pathway linking early-life adversity to depressive symptoms ...

DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

Epigenetic changes, encompassing DNA methylation, are involved in the occurrence and progression of tumors and hold promise as effective tools for screening, early diagnosis, treatment strategy, ...

Serum mucin 5AC (MUC5AC) as a predictor of outcomes and microscopic distant metastasis in pancreatic ductal adenocarcinoma (PDA). This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...

TET family of enzymes plays vital roles in DNA demethylation and the process of demethylation at the ... of new diagnostic methods and therapeutic strategies. Table 1. The role of m5C methylation ...

The methylation of plasma cell-free DNA (cfDNA) has emerged as a valuable diagnostic and prognostic biomarker in various cancers including colorectal cancer (CRC). Currently, there are no biomarkers ...

This review focuses on intergenerational and transgenerational epigenetic inheritance in different plants, animal species and ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...