The superfamily 1 (SF1) and SF2 enzymes are non-hexameric enzymes possessing both helicase and single-stranded DNA (ssDNA) translocase activities, as well as the ability to displace proteins from DNA.

topoisomerase IIα (TOP2A), in untangling the DNA threads. Second, it works with a protein called BLM helicase to convert tangled threads into a simpler, more manageable form. Together ...

This manuscript reports valuable findings on the role of the Srs2 protein in turning off the DNA damage signaling response ... In yeast, downregulation of the DNA damage checkpoint requires the Srs2 ...

Despite their genius, DNA-nanoparticle motors don't have the speed of their biological counterparts, the motor protein, which is where the issue lies. This is where researchers come in to analyze ...

Despite their potential, DNA-nanoparticle motors don't have the speed of their biological counterparts, the motor protein, which is where the issue lies. This is where researchers come in to ...

and Lausanne reveals that the protein machines that shape our DNA can switch directions. The new finding is published in Cell in an article titled, “SMC motor proteins extrude DNA asymmetrically ...

Homologous recombination is a largely error-free DNA repair mechanism conserved across all domains of life and is essential for the maintenance of genome integrity. Not only are the mutations in ...