These obstacles are evident by the large number of candidate or lead compounds failing to reach clinical trials, significantly due to a lack of efficacy in the disease paradigm of interest and/or the ...

DUBLIN--(BUSINESS WIRE)--The "Induced Pluripotent Stem Cell (iPSC) Industry Report - Market Size, Trends, & Forecasts, 2025" report has been added to ResearchAndMarkets.com's offering. Since the ...

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Ncardia’s iPSC-derived microglia may aid ALS research and help to screen new therapies that target inflammation in ALS.

Dublin, Jan. 13, 2025 (GLOBE NEWSWIRE) -- The "Induced Pluripotent Stem Cell (iPSC) Industry Report - Market Size, Trends, & Forecasts, 2025" report has been added to ResearchAndMarkets.com's ...

The versatility of induced pluripotent stem cells in regenerative medicine, disease modeling, drug discovery, and personalized therapy underpins their growing demand. Additionally, advancements in ...

22, 2025 (GLOBE NEWSWIRE) -- According to the latest study from BCC Research, “Induced Pluripotent Stem ... product functions, iPSC generation, and types of iPSC-derived cells and species.

Taken together, these data indicate that POLG mutations induced astrocytic mitophagy failure by regulating the AKT/mTOR/AMPK ... significantly increased levels for both mitophagy and lysosomal ...

Chemical biology is the study of the chemicals ... Large-scale profiling of drug-induced metabolic changes have potential for improving drug development but remain challenging.

The team validated these findings using human dopaminergic neurons derived from induced pluripotent stem cells (iPSC) and demonstrated that manganese exposure selectively damages these cells.