Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Disorders of surfactant protein biology cause ...

This marks a significant milestone as SIGX1094 is the first pipeline drug discovered using AI and organoid disease model to enter clinical trials, and the first targeted therapy candidate to ...

This marks a significant milestone as SIGX1094 is the first pipeline drug discovered using AI and organoid disease model to enter clinical trials, and the first targeted therapy candidate to address ...

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that affects an estimated 2.4 to 3.1 million people in the US alone. Despite decades of research, ...

Notably, pharmacological inhibition of PDE9A via Bay 73-6691 or virus-mediated CHIP expression restored the balance of cGMP/cAMP signalling. These interventions protect against cerebellar ...

Background: Evidence of the effectiveness of physiotherapy, including muscle strength training, coordination training, aerobic exercise, cycling regimen, balance training, gait training, and activity ...

What is a Chiari malformation? A Chiari malformation is a problem in which a part of the brain (the cerebellum) at the back of the skull bulges through a normal opening in the skull where it joins the ...

Brain tissue dysfunction caused by a growing tumor may cause other symptoms, depending on the tumor’s location. For example, if a brain tumor is located in the cerebellum at the back of the head, a ...