3. e2 increases risk for an Aβ related vessel pathology, CAA, and when CAA is present, increases risk for lobar hemorrhage. Plasma ApoE levels, insofar as they are surrogates for brain protein levels, ...

This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

Introduction: Despite a large preclinical literature demonstrating neuroprotective effects of estrogen, use of menopausal hormone therapy (HT) for Alzheimer’s disease (AD) risk reduction has been ...