The monocytic leukemia zinc-finger protein (MOZ) gene is rearranged in t(8; 16)(p11; p13) and inv(8)(p11q13) associated with acute myeloid leukemia. The other fusion partners involved are CBP and ...

C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

若弋生物是一家大分子药物递送技术研发商，专注于大分子药物递送技术的研发及其在生物医药研发中的应用。目前核心技术平台为基于锌指蛋白（Zinc Finger Proteins, ZFPs）的药物递送技术；核心在研产品为针对神经-肌肉失调类适应症的重组蛋白质药物；同时，建立了核心产品的颠覆传统方案的、基于合成生物学的新型生产工艺。近日，若弋生物完成了数千万元的Pre-A++轮融资，由高企实业投资。本轮融 ...

Meganucleases are an example of such unique sequences. The design of such enzymes that can recognize longer DNA sequences is particularly complex, however, as DNA recognition and cutting take place in ...

It has been used in a wide range of applications, from basic research to potential clinical therapies. Zinc Finger Nucleases (ZFNs) are engineered DNA-binding proteins that facilitate targeted editing ...

Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has described histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or KAT6B (MOZ2; MYST-4) ...

It does so with the help of a zinc finger, a small protein wrapped around a zinc molecule. Orkin's team has now reported the crystal structure of the BCL11A tetramer and suggested several ways to ...