Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease. In a new study published in Nature, led by scientists at the Allen ...

This discovery sheds light on how tissue-resident memory CD8 T cells adapt to their location in the body, ensuring a coordinated and effective immune response and how microenvironments and cellular ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation—and relocation—as they fight infections in the small intestine.

Your gut is a battleground. The cells that line your small intestine have to balance two seemingly contradictory jobs: absorbing nutrients from food, while keeping a wary eye out for pathogens trying ...

New types of T cells seem to pop up in the scientific literature with increasing frequency. Just this June, for instance, University of Melbourne immunologist Angela Pizzolla and her colleagues ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

When paired with 5-FU, this effect is amplified, leading to a significant infiltration of T cells into AK lesions. This process generates tissue-resident memory T cells (TRM), providing long-term ...