Rising diagnoses of certain cancers in people under 50 predate the rollout of COVID-19 vaccines by decades, undermining ...
The activation of the intracellular transmembrane receptor stimulator of interferon genes (STING) has shown antitumoral effects in murine cancer models.
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Metalloimmunotherapy: Combination of cisplatin and STING agonist into one molecule boosts cancer immune responseMore information: Shuren Zhang et al, Combining cisplatin and a STING agonist into one molecule for metalloimmunotherapy of cancer, National Science Review (2024). DOI: 10.1093/nsr/nwae020 ...
Researchers at the Terasaki Institute for Biomedical Innovation have developed an innovative delivery system that could significantly improve the effectiveness of peptide-based cancer vaccines, ...
STING drives pro-inflammatory interferon cytokine production when double-stranded DNA is present in the cytosol, something that only happens in cancer cells. In 2013, a synthetic STING agonist, ...
(10) Recent unpublished data revealed that immunization with CPAF covalently conjugated to a novel STING agonist provided equivalent immunogenicity and protection to admixture using 25-fold less ...
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