Although scleroderma is rare ... As the disease progresses, the skin on the hands and feet undergoes significant changes, ...

Scleroderma is classified as a rare, autoimmune, collagen-vascular disease of unknown etiology that can be difficult to diagnose and treat. Its onset can be insidious or rapid; the symptoms range ...

Scleroderma is a rare disease in which a person's immune system begins to destroy ... The fingers and hands (or, more rarely, the feet, nose, or ears) may turn pale, white, and later blue and feel ...