The FDA announced the approval of a new treatment for pneumonia caused by certain difficult-to-treat bacteria, offering hope ...

Trial results demonstrated that the peptide was at least as effective as conventional antibiotics, but did not show it was significantly better. As a result, the FDA refused approval in July.

Discover the importance of antibiotics, bacterial cell walls, and resistance mechanisms in fighting bacterial infections effectively.

Antibiotic-resistant bacteria have become a major threat to public health. The World Health Organization estimates that 1.27 ...

To enable clinical use for the peptide material, particularly in combination with standard treatments such as antibiotics, the researchers had to ensure that the material does not negatively ...

July 2, 2024 — A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making ...

New research published today in Nature Communications, describes how CRISPR-Cas9 gene editing can be used to create new nonribosomal peptide synthetase (NRPS) enzymes that deliver clinically important ...

These peptides are especially effective against a wide range of bacteria, including some strains known for their resistance to conventional antibiotics. One of the key peptides identified in Rana ...

For technical reasons, the English full text will be published approximately two weeks after the German print edition has been published. 1. Hornef MW, Wick MJ, Rhen M et al.: Bacterial strategies ...

Keywords structure function and engineering of polyketide synthases hybrid polyketide/non-ribosomal peptide antibiotics and anticancer drugs polyketide based cholesterol lowering agents Areas of ...