The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...

It is important to note that although we have some idea about the propagation of DNA methylation and models are emerging for the duplication of histone PTMs, very little is known about the ...

Researchers discovered a molecular timer that gets activated in the first days of pregnancy and influences when mice give ...

There are several different types of heritable epigenetic marks or modifications, the most established and well-researched of which are histone modifications and DNA methylation. “What's exciting ...

"When histone methylation erodes enough, nearby genes flip on." When the researchers blocked KDM6B, histones near certain genes accumulated too much methylation early in pregnancy. This increased ...

“When histone methylation erodes enough, nearby genes flip on.” When the researchers blocked KDM6B, histones near certain genes accumulated too much methylation early in pregnancy. This ...

Methylation at H3K4 promotes transcription of genes near the histone, and marking H3Q5 with a serotonin helps maintain that methylation and gene expression. Marking H3Q5 with a histamine does the ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. In a recent study published in the journal Science Advances ...

DNA methylation, and histone modifications. Under Iestyn’s leadership, Richard Koche has been appointed as the Head of ERIL and leader of the computational unit and Pierre-Jacques Hamard has been ...

These are chemical changes to DNA or histone proteins that do not alter the DNA sequence itself but affect how genes are expressed. Examples include DNA methylation and histone acetylation, which can ...