The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in the January 2025 issue of Allergy and Immunology by Pan et al. Epigenetic ...

Researchers discovered a molecular timer that gets activated in the first days of pregnancy and influences when mice give ...

A typical human pregnancy lasts 40 weeks, but most parents know this number is only a rough estimate. Babies are born on a seemingly unpredictable timeline, with a normal pregnancy ranging from 38 to ...

The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...

Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

Sen and her colleagues studied fragments containing cryptic sites and compared the levels of histone methylation, which winds up DNA and switches it “off” by making it unavailable for transcription, ...

There are several different types of heritable epigenetic marks or modifications, the most established and well-researched of which are histone modifications and DNA methylation. “What's exciting ...

Methylation at H3K4 promotes transcription of genes near the histone, and marking H3Q5 with a serotonin helps maintain that methylation and gene expression. Marking H3Q5 with a histamine does the ...

“When histone methylation erodes enough, nearby genes flip on.” When the researchers blocked KDM6B, histones near certain genes accumulated too much methylation early in pregnancy. This ...