Genome-wide association (GWA) studies have identified large numbers of genetic variants that contribute to disease risk. Most GWA studies have been performed primarily in populations of European ...
Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes. But ...
大规模 DNA 测序技术的发展使人们能够获取大量基因型信息,但如何阐释基因型对人类生物学的多样化影响成为新挑战。将人类基因和基因型与疾病及性状相关表型系统地联系起来,仍是生物医学领域的重大难题。
引言在基因组学快速发展的今天,我们已经能够通过大规模DNA测序技术精确识别和分类人类基因的多样性。然而,如何将基因型与其在生物学中的功能和疾病表型相联系,仍然是生命科学领域的一大挑战。现有的方法虽能在一定程度上揭示基因功能,但往往局限于简单的现象,比 ...
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
A research team at the Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences employed genome-wide association analysis to detect a major effect, coded QTL-qVE.C02, which is ...
The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...
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