The accuracy of these copies determines the health and inherited features of the nascent cells, so it is essential that the process of DNA replication be as accurate as possible (Figure 1).

as replication fork proteins can collide with them and become displaced from DNA. These include various DNA binding proteins such as the transcription machinery. Another physical barrier could be ...

Each strand serves two primary purposes: acting as a template during DNA replication and providing instructions for protein synthesis in a process called transcription. Replication and ...

DNA replication is the process by which the DNA molecule makes ... DNA polymerase enzymes facilitate this process, ensuring accurate copying of the genetic information. Transcription is the process by ...

In fact, the DNA molecule is usually folded back on itself several times to fit inside the cell nucleus and is only 'relaxed' ...

Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA ...

The process is made up of the transcription and translation of DNA sequences. Genome and mutations DNA replication is carefully controlled to preserve the genetic information. However, changes in ...

Transcription factors are proteins that can bind to DNA and affect the expression of genes; some are known as master regulators that can have a wide impact | Genetics And Genomics ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

This important study presents compelling observational data supporting a role for transcription and polysome accumulation in the separation of newly replicated bacterial chromosomes. The study is ...