ATR and ATM kinases are key factors for the surveillance of DNA replication, and prevent chromosome breakage in dividing cells. However, during repair processes, chromosome fragments can be ...

Processes such as transcription and replication require the two ... Comparing the length of metaphase chromosomes to that of naked DNA, the packing ratio of DNA in metaphase chromosomes is ...

We have also argued that unlinking of the sister chromosomes during DNA replication is aided by removal of pre-catenanes that are forming directly at or just behind the replication fork (Fig. 8) and ...

Your chromosomes are how your cells store your DNA. They also help ensure the accurate copying of DNA during cell replication. This DNA is grouped into segments called genes. Your genes determine ...

After DNA replication, chromosomes consist of two identical copies of the genetic material “glued” together. During mitosis, or M-phase, the “glued” chromosomes (sister chromatids) align on a scaffold ...

We are interested in the mechanism of chromosome replication, a process that is highly conserved across eukaryotes and that involves the duplication of both the chromosomal DNA and its associated ...

The nucleus of each human body cell contains 46 chromosomes. Each chromosome contains about 1000 genes. There is enough DNA in all the cells in a human body to stretch to the sun and back again ...

Each cell with a nucleus contains chromosomes, which are made from DNA Human body cells each contain 23 pairs of chromosomes, half of which are from each parent. So, human gametes (eggs and sperm ...

In addition to shelterin, telomeric DNA is also wrapped around histone octamers in a closed, heterochromatic state that compacts telomeric DNA and represses transcription at the chromosome end (Tardat ...

So, it's very easy to see,” she said. To zoom in on changes in chromosome organization during meiosis, the researchers used nuclear membrane and DNA damage protein stains to track nuclear behavior.

The Homo sapiens genome today contains a little bit of Neanderthal DNA. These genetic traces come from almost every part of ...