‹1› Braidy N, Guillemin GJ, Mansour H, et al . Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One 6: e19194, 2011. ‹2›Camacho-Pereira J, Tarragó MG, ...

赛诺菲今日宣布，旗下抗CD38单抗赛可益 ® （艾沙妥昔单抗注射液）获得国家药品监督管理局（NMPA）批准，用于与泊马度胺和地塞米松联合用药 ...

Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...

ART1- mediated ADP-ribosylation of T cells can trigger an apoptotic cascade resulting in NAD-induced cell death (NICD), and subsequently tumour immune escape [2]. The ectonucleotidase CD38, is ...

中国网财经1月25日讯 赛诺菲抗CD38单抗赛可益(艾沙妥昔单抗注射液)昨日获得国家药监局(NMPA)批准，用于与硼替佐米、来那度胺和地塞米松(VRd ...

1月24日，赛诺菲抗CD38单抗艾沙妥昔单抗注射液（商品名：赛可益）获得国家药品监督管理局（NMPA）批准，用于与硼替佐米、来那度胺和地塞米松 ...

FK866 potently inhibited NAMPT activity as demonstrated by reduced mucosal NAD, resulting in reduced abundances and activities of NAD-dependent enzymes including PARP1, Sirt6 and CD38, reduced nuclear ...

charite.de We recently reported the successful treatment of two systemic lupus erythematosus (SLE) patients with daratumumab, a CD38-targeting human monoclonal antibody, demonstrating a clinically ...

CARsgen Therapeutics Holdings Limited, a company focused on innovative CAR T-cell therapies for the treatment of hematologic malignancies and solid tumours, announces that KJ-C2320, an allogeneic CAR ...