Objective Metabolic reprogramming plays a critical role in modulating the innate and adaptive immune response, but its role ...
ART1- mediated ADP-ribosylation of T cells can trigger an apoptotic cascade resulting in NAD-induced cell death (NICD), and subsequently tumour immune escape [2]. The ectonucleotidase CD38, is ...
强生达雷妥尤单抗进入“百亿美元俱乐部”几乎已无悬念之际,蓄势已久的CD38药物终于在2025年开年展现出了燎原态势。 2025年的第二周,CD38靶点 ...
U.S.-based biotech builder Mountainfield Venture Partners and China’s Keymed Biosciences have launched a new company armed with $180 million in series A funds and a clinical-stage CD38-targeting ...