they transitioned the astrocytes to a pathogenic state by adding microglia-derived cytokines, which are the molecular cues that induce reactivity in neurodegenerative diseases. 2 Using this system to ...

Others have produced little spheres of human neural tissue by combining neurons, astrocytes, and microglia, all derived from induced pluripotent stem cells. Neurons in this system were more active ...

We use induced pluripotent stem cells (iPSCs) representing neurological and psychiatric diseases. Differentiation of iPSCs into neurons, astrocytes, microglia allow us to analyze aberrant gene and ...

Alongside microglia, astrocytes play a pivotal role in supporting brain functions, including metabolism, neurotransmitter ...

During development, there are known sex-related differences in how microglia function. But into adulthood, there was thought to be less variation in how they behave. Microglia maintain neuronal ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Brain support cells called astrocytes have long been found around glioblastomas, leading scientists to think that the cells rally to help fight the tumors, but recent studies have found that the cells ...

Astrocytes are star-shaped glial cells in ... "With our colleagues at AbbVie Inc, we also studied progression of microglia, endothelial, and neuronal cells in AD," added Das.