生物通11 天
APOE4和久坐生活方式协同损害清醒小鼠视觉皮层的神经血管功能
生活方式与遗传性阿尔茨海默病的风险有关：老鼠血管和神经元的体内成像显示，当神经元活跃、老鼠运动较少时，APOE4在已经紧张的系统中最能降低神经血管功能。 APOE4 基因与生活方式对神经血管功能的协同影响研究解读 英国萨塞克斯大学心理学与萨塞克斯 ...
Nature8 年
Metabolic shifts toward fatty-acid usage and increased thermogenesis are associated with ...
The Apolipoprotein E (APOE) gene encodes for three isoforms in the human population (APOE2, APOE3 and APOE4). Whereas the role of APOE in lipid metabolism is well characterized, the specific ...
来自MSN9 个月
Study reveals that almost all individuals with two copies of the APOE4 gene develop signs ...
Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene—APOE4 ...